| Wednesday 20 September 2006 |
| |
| Acharnaikos v Kastoria (15:30 BST) | 3.60 | 3.15 | 2.20 | 105% | |
| AE Giannina v Thrasevoylos Fylis (15:30 BST) | 4.33 | 3.40 | 2.00 | 103% | |
| Anagennisi Artas v Kallithea (15:30 BST) | 5.25 | 3.50 | 1.70 | 107% | |
| Apollon Smyrnis v Agrotikos (15:30 BST) | 3.40 | 3.15 | 2.00 | 112% | |
| Atsalenios v Ethnikos Asteras (15:30 BST) | 2.55 | 3.10 | 2.90 | 106% | |
| Diagoras v Ilisiakos (15:30 BST) | 2.80 | 3.15 | 2.65 | 106% | |
| Eolikos Mytilinis v Messiniakos (15:30 BST) | 2.85 | 3.00 | 2.30 | 112% | |
| Ierapetra v Chaidari (15:30 BST) | 3.50 | 3.15 | 2.00 | 111% | |
| Olympiakos Volou v Proodeytiki (15:30 BST) | 2.70 | 3.00 | 3.00 | 104% | |
| Panetolikos v Ethnikos Ach (15:30 BST) | 2.60 | 3.15 | 2.40 | 112% | |
| Paniliakos v Veroia (15:30 BST) | 4.00 | 3.30 | 1.80 | 111% | |
| PAO Neon Epivaton v Levadiakos (15:30 BST) | 5.00 | 3.60 | 1.60 | 111% | |
| Pierikos v Kalamata (15:30 BST) | 2.15 | 3.20 | 3.60 | 106% | |
| Thiva v Panahaiki 2005 (15:30 BST) | 2.55 | 3.10 | 2.85 | 107% | |
| Thyela Patron v Niki Volou (15:30 BST) | 2.40 | 3.15 | 2.60 | 112% | |
| Vizas Megaron v PAS Giannina (15:30 BST) | 6.50 | 4.00 | 1.65 | 101% | |